Articles 2004-2009

The following manuscripts were published as a Master student, PhD student and Postdoctoral fellow at MRC-LMB (UK), MPG Halle (DE), Brandeis University (US), FLI Jena (DE), University of Jena (DE).

2009

• 10. Low, H.H., Sachse, C., Amos, L.A., and Löwe, J. (2009). Structure of a bacterial dynamin-like protein lipid tube provides a mechanism for assembly and membrane curving. Cell 139, 1342–1352.
• 9. Meinhardt, J., Sachse, C., Hortschansky, P., Grigorieff, N., and Fändrich, M. (2009). Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils. J Mol Biol 386, 869–877.
• 8. Schmidt, M., Sachse, C., Richter, W., Xu, C., Fändrich, M., and Grigorieff, N. (2009). Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures. Proc Natl Acad Sci USA 106, 19813–19818.

2008

• 7. Chen, J.Z., Sachse, C., Xu, C., Mielke, T., Spahn, C.M.T., and Grigorieff, N. (2008). A dose-rate effect in single-particle electron microscopy. J Struct Biol 161, 92–100.
• 6. Sachse, C., Fändrich, M., and Grigorieff, N. (2008). Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy. Proc Natl Acad Sci USA 105, 7462–7466.

2007

• 5. Habicht, G., Haupt, C., Friedrich, R.P., Hortschansky, P., Sachse, C., Meinhardt, J., Wieligmann, K., Gellermann, G.P., Brodhun, M., Götz, J., et al. (2007). Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils. Proc Natl Acad Sci USA 104, 19232–19237.
• 4. Sachse, C., Chen, J.Z., Coureux, P.-D., Stroupe, M.E., Fändrich, M., and Grigorieff, N. (2007). High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus. J Mol Biol 371, 812–835.

2006

• 3. Sachse, C., Xu, C., Wieligmann, K., Diekmann, S., Grigorieff, N., and Fändrich, M. (2006). Quaternary structure of a mature amyloid fibril from Alzheimer’s Abeta(1-40) peptide. J Mol Biol 362, 347–354.

2005

• 2. Glaser, R.W., Sachse, C., Dürr, U.H.N., Wadhwani, P., Afonin, S., Strandberg, E., and Ulrich, A.S. (2005). Concentration-dependent realignment of the antimicrobial peptide PGLa in lipid membranes observed by solid-state 19F-NMR. Biophys. J. 88, 3392–3397.

2004

• 1. Glaser, R.W., Sachse, C., Dürr, U.H.N., Wadhwani, P., and Ulrich, A.S. (2004). Orientation of the antimicrobial peptide PGLa in lipid membranes determined from 19F-NMR dipolar couplings of 4-CF3-phenylglycine labels. J. Magn. Reson. 168, 153–163.